Registration Dossier
Registration Dossier
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EC number: 250-195-3 | CAS number: 30431-54-0
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 999
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Subdivision F, guideline REF. #81-1
- GLP compliance:
- yes
- Test type:
- standard acute method
- Limit test:
- no
Test material
- Reference substance name:
- Bis(2,4,5-trichloro-6-carbopentoxyphenyl) oxalate
- EC Number:
- 250-195-3
- EC Name:
- Bis(2,4,5-trichloro-6-carbopentoxyphenyl) oxalate
- Cas Number:
- 30431-54-0
- Molecular formula:
- C26H24Cl6O8
- IUPAC Name:
- pentyl 2,3,5-trichloro-6-[(2-oxo-2-{3,4,6-trichloro-2-[(pentyloxy)carbonyl]phenoxy}acetyl)oxy]benzoate
- Reference substance name:
- Butyl benzoate
- EC Number:
- 205-252-7
- EC Name:
- Butyl benzoate
- Cas Number:
- 136-60-7
- Molecular formula:
- C11H14O2
- IUPAC Name:
- butyl benzoate
- Test material form:
- liquid
Constituent 1
Constituent 2
Test animals
- Species:
- rat
- Strain:
- Sprague-Dawley
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- unchanged (no vehicle)
- Doses:
- 2500， 3200， 5000 mg/kg
- No. of animals per sex per dose:
- 15
- Control animals:
- no
Results and discussion
Effect levels
- Key result
- Dose descriptor:
- LD50
- Effect level:
- > 3 200 - < 5 000 mg/kg bw
- Based on:
- test mat.
- Mortality:
- No mortality was observed at 2500 or 3200 mg/Kg. Seven of ten animals were found dead at 5000 mg/Kg.
- Clinical signs:
- other: Decreased activity, decreased muscle tone, abnormal gait, abnormal stance, discolored fur (green or yellow) and poor grooming were observed in the animals at 3200 and 5000 mg/Kg. Prostration was also observed at 5000 mg/Kg with loose stool and yellow stai
- Other findings:
- No visible lesions were observed in the surviving animals at terminal necropsy. Necropsy of animals found dead revealed distended stomachs, red lesions in the stomachs, and fluid-filled red intestines.
Applicant's summary and conclusion
- Interpretation of results:
- other: not classified according to CLP Regulation
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