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There are acute aquatic toxicity studies available for three trophic levels. The test substance was acutely harmful to fish while it was acutely not toxic to aquatic invertebrates or green algae, respectively.

Based on the results from these three study reports, 1,3 -Propanediol, 2,2 -dimethyl-, 1,3 -diacetate is considered as acutely harmful to aquatic organisms.