Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
other: Expert Statement
Adequacy of study:
weight of evidence
Study period:
Aug. 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Expert Statement from GLP accredited testing Laboratory

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guideline
Qualifier:
no guideline required
Principles of method if other than guideline:
Expert statement regarding the partition coefficent testing
GLP compliance:
yes
Type of method:
other: Not applicable
Partition coefficient type:
other: Not applicable

Test material

Constituent 1
Reference substance name:
Petroleum resins
EC Number:
265-116-8
EC Name:
Petroleum resins
Cas Number:
64742-16-1
Molecular formula:
UVCB substance containing saturated aliphatic hydrocarbon and aromatic hydrocarbons
IUPAC Name:
naphthalene
Test material form:
liquid
Details on test material:
Reference Name: Petroleum Resins (Kendex 0897)
Sponsor Information: CAS Number 64742-16-1
Label Identification: LANXESS Lot # E267112117, 18 Jan 18, Kendex 0897
Quantity & Date Received: 24 Jan 18; 76.1 g (GW)
Physical Description: Brown liquid
Storage: Room temperature
Purity: See Certificate of Analysis
Stability: Not provided to testing facility
Specific details on test material used for the study:
No further details specified in the statement

Study design

Analytical method:
other: Not applicable

Results and discussion

Partition coefficient
Remarks on result:
not determinable because of methodological limitations
Details on results:
The test item Petroleum Resins (Kendex 0897) is a UVCB substance. Solubility tests showed that the test item is not soluble in acetonitrile, methanol or isopropanol at target concentration 1 g/L.
For experimental determination of the log Pow, completely dissolved materials is a prerequisite. As a consequence, the determination is not possible using the HPLC method according to OECD 177. Other available methods (OECD 107, shake flask method and OECD 123, slow stirring method) are only acceptable to pure substances and cannot be performed either.

Applicant's summary and conclusion

Conclusions:
The test item Petroleum Resins (Kendex 0897) is a UVCB substance. Solubility tests showed that the test item is not soluble in acetonitrile, methanol or isopropanol at target concentration 1 g/L.
For experimental determination of the log Pow, completely dissolved materials is a prerequisite. As a consequence, the determination is not possible using the HPLC method according to OECD 177. Other available methods (OECD 107, shake flask method and OECD 123, slow stirring method) are only acceptable to pure substances and cannot be performed either.
Executive summary:

The test item Petroleum Resins (Kendex 0897) is a UVCB substance. Solubility tests showed that the test item is not soluble in acetonitrile, methanol or isopropanol at target concentration 1 g/L.

For experimental determination of the log Pow, completely dissolved materials is a prerequisite. As a consequence, the determination is not possible using the HPLC method according to OECD 177. Other available methods (OECD 107, shake flask method and OECD 123, slow stirring method) are only acceptable to pure substances and cannot be performed either.