Registration Dossier
Registration Dossier
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EC number: 700-636-5 | CAS number: 5413-49-0
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (48h) = 447 mg/l
NOEC (48h) = 232 mg/l
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 447 mg/L
Additional information
The potential of the test substance to cause acute toxic effects to aquatic invertebrates was evaluated according to EPA Method OPPTS 850. 1010. Five neonated Daphnia pulex were exposed to each concentration of the test substance, under static conditions, for 48 hours.
Laboratory control water for tests consisting of an 80% : 20% mixture of Type 1 laboratory water and a commercial spring water (Perrier) was used. Observations were made on the immobilisation, after 24 and 48 h of exposure. Based on the results of the range-finding study, a six concentration of four replicates (5 daphnids/vessel) was selected for the definitive test (31.25, 62.5, 125, 250, 500, and 1000 mg/l).
There were no statistically significant reductions in mobility at 24 h up to the measured concentration of 957 mg/l; the 24 h EC50 was > 957 mg/l. However, there was a statistically significant reduction in mobility at 48 h at the measured concentration of 478 mg/l. The 48 h EC50 was determined to be 447 mg/l. Under the test conditions, the 48 h EC50 value of the test substance was determined to be 447 mg/l with a NOEC (No Observed Effect concentration) of 232 mg/l.
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