Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-613-9 | CAS number: 144-02-5
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
There are 2 studies dealing with the kinetics of barbital sodium. Both have no sufficient reliability.
The toxicokinetic investigations revealed:
- The transfer of sodium barbital from the mother to the embryo takes place within the first fifteen minutes after the injection. The concentration of the barbiturate may reach a fairly high level in the fetus. The placenta presents no barrier to the passage of barbital into the embryo.- The averages of the logarithms of barbital sodium blood levels obtained in six dogs, kept alternately at 15°C room temperature and 30°C room temperature, after an i.v. injection of 150 mg/kg barbital sodium, showed no significant difference at the two temperatures for the slope functions or for the intersection point with the time.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
