Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 610-565-0 | CAS number: 50717-99-2
Endpoint summary
Administrative data
Description of key information
In a reliable 48 -h acute toxicity study with Daphnia magna performed with a structural analogue of Norethylac, Norethyl, the 48 -h EC50 was above the solubility limit of the substance (>0.064 mg/L). This result can be read across to Norethylac.
In a reliable 72 -hr toxicity study with freshwater algae conducted with a structural analogue of Norethylac, Norethyl, the 72 -h ERC50 was > 0.0014 mg/L based on TWA concentrations. This result can be read across to Norethylac.
Additional information
In a 48h acute toxicity study with a structural analogue of Norethylac, Norethyl, conducted according to OECD guideline 202, Daphnia magna were exposed to Norethyl under static conditions at the following nominal concentrations: 0 (Control), 10, 18, 32, 56, and 100% of the Saturated Solution prepared at a loading rate of 100 mg/L. The geometric mean measured concentration in the SS was calculated to be 0.064 mg/L, which was considered the solubility limit in test medium. No immobility was observed at any of the test concentrations and the control during the exposure period. Therefore, the 48h-EC50 was above the solubility limit, i.e. >0.064 mg/L. The study is considered to be reliable without restrictions. This result can be read across to Norethylac.
In a 72 h toxicity study conducted according to OECD guideline 201 and GLP principles with a structural analogue of Norethylac, Norethyl, freshwater algae (Pseudokirchneriella subcapitata) were exposed to Norethyl at a nominal loading rate of 100 mg/L (saturated solution) and an untreated control. Exposure concentration was verified by a validated analytical method to be 0.0014 mg/L (TWA). No inhibition of growth rate was recorded at the concentration of Norethyl tested. The 72h-ERC50 was >0.0014 mg/L and the 72h-NOEC was 0.0014 mg/L, based on TWA concentrations. The study is considered to be reliable without restrictions. This result can be read across to Norethylac.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
