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Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Study period:
February 03,2017 - March 17,2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
Deviations:
no
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
Aluminum magnesium sodium oxide (Al10.33Mg0.67Na1.67O17)
EC Number:
807-888-6
Cas Number:
110621-40-4
Molecular formula:
Al10.33Mg0.67Na1.67O17
IUPAC Name:
Aluminum magnesium sodium oxide (Al10.33Mg0.67Na1.67O17)

Sampling and analysis

Analytical monitoring:
yes
Details on sampling:
The test solutions were collected from each loading rate, the negative control and the WSF control at test initiation and at test completion.

Test solutions

Vehicle:
no
Details on test solutions:
The test item is a difficult item as defined by the OECD Guideline 23 (2000) because it isa multicomponent substance with low water solubility. In order to maximise the amount of test item in solution, the test solutions were prepared as water soluble
fractions (WSF) using the methodology described below.
Water soluble fractions (WSFs) were prepared at 6.25, 12.5, 25, 50, and 100 mg/Lnominal loading rates and tested alongside a negative control and a WSFcontrol.

Test organisms

Test organisms (species):
Daphnia magna
Details on test organisms:
In‐house culture; original culture was obtained from Aquatic BioSystems (Fort Collins, CO) in April 2016(identified by EcoAnalysts Inc. on March 10, 2016 as D.magna)

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h

Test conditions

Hardness:
88 mg/L CaCO3
Test temperature:
21.9 °C
pH:
8.2
Dissolved oxygen:
8.6 mg/L
Conductivity:
313 µS/cm
Nominal and measured concentrations:
Nominal loading rates of the test item: 6.25, 12.5, 25.0, 50.0 and 100 mg/L
Measured Loading Rates of Aluminium: 0.02, 0.07, 0.14, 0.28 0.53 mg/L

Results and discussion

Effect concentrationsopen allclose all
Key result
Duration:
48 h
Dose descriptor:
EL50
Effect conc.:
75.17 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Key result
Duration:
48 h
Dose descriptor:
NOELR
Effect conc.:
50 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility

Applicant's summary and conclusion