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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
other: official database
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
Isopropyl nitrite
Author:
ACToR - EPA
Year:
1966
Bibliographic source:
Gigiena Truda i Professionalnye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 10(10), Pg. 29, 1966
Reference Type:
review article or handbook
Title:
Isopropyl nitrite
Author:
ACToR - EPA
Year:
1982
Bibliographic source:
Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure, Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 79, 1982

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Data from handbook
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Isopropyl nitrite
EC Number:
208-779-0
EC Name:
Isopropyl nitrite
Cas Number:
541-42-4
Molecular formula:
C3H7NO2
IUPAC Name:
propan-2-yl nitrite

Results and discussion

Effect levelsopen allclose all
Dose descriptor:
LC50
Effect level:
ca. 2 800 mg/m³ air
Key result
Dose descriptor:
LC50
Effect level:
ca. 1 250 mg/m³ air

Applicant's summary and conclusion

Interpretation of results:
Category 2 based on GHS criteria