Registration Dossier
Registration Dossier
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EC number: 221-361-2 | CAS number: 3077-27-8
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
Reference
Description of key information
Based on the amid group hydrolysis might be possible but with the exception of a few halogenated acetamides, most amides hydrolyze to acids extremely slowly at 25 °C and pH7 with half-lives measured in centuries with the exception of only a few halogenated acetamides (Hydrowin v2.00). Therefore hydrolysis of 4-(octadecylamino)-4-oxoisocrotonic acid (CAS 3077-27-8) is not considered to be a relevant degradation pathway in the environment.
Key value for chemical safety assessment
Additional information
No experimental studies investigating the abiotic hydrolysis of 4-(octadecylamino)-4-oxoisocrotonic acid (CAS 3077-27-8) are available. However, based on the amid group hydrolysis might be possible but with the exception of a few halogenated acetamides, most amides hydrolyze to acids extremely slowly at 25 °C and pH7 with half-lives measured in centuries with the exception of only a few halogenated acetamides (Hydrowin v2.00). Therefore hydrolysis of 4-(octadecylamino)-4-oxoisocrotonic acid (CAS 3077-27-8) is not considered to be a relevant degradation pathway in the environment.
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