Registration Dossier
Registration Dossier
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EC number: 612-381-6 | CAS number: 61789-91-1
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 988
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Federal Hazardous Substance Act, 16 CFR Section 1500.41
- GLP compliance:
- not specified
Test material
- Reference substance name:
- no defined IUPAC name
- EC Number:
- 612-381-6
- Cas Number:
- 61789-91-1
- Molecular formula:
- no molecular structure defined
- IUPAC Name:
- no defined IUPAC name
- Details on test material:
- Components Floraesters 60
Wax Ester ---
36:2 <2
38:0 1 - 3
38:1 2 - 4
38:2 1.5 - 4
40:0 7 - 18
40:1 18 - 20
40:2 5 - 15
42:0 6 - 15
42:1 16 - 21
42:2 4 - 12
44:0 2 - 5
44:1 4 - 7
44:2 1 - 4
46:2 <3
Iodine Value** 40 - 44
Mono-ester content*** 46 - 53
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
Test system
- Type of coverage:
- occlusive
- Preparation of test site:
- clipped
- Vehicle:
- unchanged (no vehicle)
- Controls:
- not required
- Duration of treatment / exposure:
- 24 h
- Observation period:
- 24 and 72 h
- Number of animals:
- 6
Results and discussion
In vivo
Results
- Irritation parameter:
- primary dermal irritation index (PDII)
- Basis:
- mean
- Time point:
- other: 24/72h
- Score:
- ca. 1.08
- Max. score:
- 1.83
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The test material as submitted, when tested as described, would not be classified as a primary skin irritant as defined by the Federal Hazardous Substances Act, 16 CFR, Section 1500.3 (c) (4).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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