Registration Dossier
Registration Dossier
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EC number: 226-518-9 | CAS number: 5417-35-6
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 15.11 - 21.11.2000
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study performed according to OECD and GLP guidelines
Cross-reference
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 000
- Report date:
- 2000
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 4,7-dihydro-2-isopropyl-1,3-dioxepin
- EC Number:
- 226-518-9
- EC Name:
- 4,7-dihydro-2-isopropyl-1,3-dioxepin
- Cas Number:
- 5417-35-6
- Molecular formula:
- C8H14O2
- IUPAC Name:
- 2-(propan-2-yl)-4,7-dihydro-2H-1,3-dioxepine
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 24 h
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- 760 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: 95% CL 630 - 900 mg/l
- Duration:
- 24 h
- Dose descriptor:
- EC100
- Effect conc.:
- 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 24 h
- Dose descriptor:
- NOELR
- Effect conc.:
- 460 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
Any other information on results incl. tables
no other information
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The 24h EC50 value for this substance is 760 mg/l (nominal). The 95% CL range is 630 - 900 mg/l
- Executive summary:
The 24h EC50 value for this substance is 760 mg/l (nominal). The 95% CL range is 630 - 900 mg/l
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