Registration Dossier
Registration Dossier
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reaction mass of mono to tetra(lithium and/or sodium)3-amino-10-[4-(4-amino-3-sulfonatoanilino)-6-[methyl-(2-sulfonatoethyl)amino]-1,3,5-triazin-2-ylamino]-6-13-dichlorobenzo[1,2-B:4,5-B']di[1,4]benzoxazine-4,11-disulfonate; mono to tetra(lithium and/or sodium)3-amino-10-[4,6-bis(4-amino-3-sulfonatoanilino)-1,3,5-triazin-2-ylamino]-6-13-dichlorobenzo[1,2-B:4,5-B']di[1,4]benzoxazine-4,11-disulfonate; mono to penta(lithium and/or sodium)10,10´-diamino-6,6',13,13´-tetrachloro-3,3'-[6-[methyl-(2-sulfonatoethyl)amino]-1,3,5-triazin-2,4-diyldiimino]bis[benzo[1,2-B:4,5-B']di[1,4]benzoxazine-4,11-disulfonate; mono to hepta(lithium and/or sodium)10-amino-6,6',13,13'-tetrachloro-10´[4-(4-amino-3-sulfonatoanilino)-[6-methyl-(2-sulfonatoethyl)amino]-1,3,5-triazin-2,4-diimino]bis[benzo[1,2-B:4,5-B']di[1,4]benzoxazine-4,11-disulfonate; mono to hepta(lithium and/or sodium)10,10'-diamino-6,6',3,3'[(2-sulfonato)-1,4-phenylenediiminobis[6-methyl-(2-sulfonatoethyl)amino]-1,3,5-triazin-2,4-diyldiimino]bis[benzo[1,2-B:4,5-B']di[1,4]benzoxazine-4,11-disulfonate
EC number: 430-200-7 | CAS number: -
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 998
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 401 (Acute Oral Toxicity)
- GLP compliance:
- yes
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- -
- EC Number:
- 430-200-7
- EC Name:
- -
- IUPAC Name:
- tridecalithium(1+) tetradecasodium 3-({4-[(4-amino-3-sulfophenyl)amino]-6-[methyl(2-sulfoethyl)amino]-1,3,5-triazin-2-yl}amino)-10-({4-[(10-amino-6,13-dichloro-4,11-disulfo-5,12-dioxa-7,14-diazapentacen-3-yl)amino]-6-[methyl(2-sulfoethyl)amino]-1,3,5-triazin-2-yl}amino)-6,13-dichloro-5,12-dioxa-7,14-diazapentacene-4,11-disulfonate 3-amino-10-({4,6-bis[(4-amino-3-sulfophenyl)amino]-1,3,5-triazin-2-yl}amino)-6,13-dichloro-5,12-dioxa-7,14-diazapentacene-4,11-disulfonate 3-amino-10-({4-[(10-amino-6,13-dichloro-4,11-disulfo-5,12-dioxa-7,14-diazapentacen-3-yl)amino]-6-[methyl(2-sulfoethyl)amino]-1,3,5-triazin-2-yl}amino)-6,13-dichloro-5,12-dioxa-7,14-diazapentacene-4,11-disulfonate 3-amino-10-({4-[(4-amino-3-sulfophenyl)amino]-6-[methyl(2-sulfoethyl)amino]-1,3,5-triazin-2-yl}amino)-6,13-dichloro-5,12-dioxa-7,14-diazapentacene-4,11-disulfonate 3-amino-10-[(4-{[4-({4-[(10-amino-6,13-dichloro-4,11-disulfo-5,12-dioxa-7,14-diazapentacen-3-yl)amino]-6-[methyl(2-sulfoethyl)amino]-1,3,5-triazin-2-yl}amino)-2-sulfophenyl]amino}-6-[methyl(2-sulfoethyl)amino]-1,3,5-triazin-2-yl)amino]-6,13-dichloro-5,12-dioxa-7,14-diazapentacene-4,11-disulfonate
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- water
- Remarks:
- bi-distilled
- Details on oral exposure:
- concentration: 0.2 g/ml; amount of vehicle: 10 ml/kg;
- Doses:
- 2000 mg/kg bw;
- No. of animals per sex per dose:
- 5 per sex per dose
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Based on:
- test mat.
- Mortality:
- Male: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0 Female: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0
- Clinical signs:
- no clinical signs of toxicity were observed
- Body weight:
- the body weight was within the range commonly recorded.
- Gross pathology:
- no macroscopic findings;
- Other findings:
- none reported;
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- not subject of classification
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