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Diss Factsheets

Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
27 July 1995
Deviations:
no
GLP compliance:
no
Other quality assurance:
ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
Type of method:
flask method
Specific details on test material used for the study:
Batch No.: 4425-191127
Purity: 99.8%
Remarks on result:
not determinable
Remarks:
severely hydrolyzed, exact water solubility could not be given
Details on results:
Based on HPLC analysis results, when the solvent is acetonitrile, the normalized area content of the test substance is 98.6%, while in the water solubility experiment, the content of the test substance after shaking for 24 h and 72 h were only 2.58% and 1.21%, respectively. It is indicated that the test item was severely hydrolyzed and the exact water solubility could not be given.
Conclusions:
The water solubility of test item could not be gived as it severely hydrolyzed.
Executive summary:

The water solubility of test item was determined with flask method, which was compatible with OECD 105. 


The water solubility of test item could not be given as it severely hydrolyzed.

Description of key information

The water solubility of test item was determined with flask method, which was compatible with OECD 105. 


The water solubility of test item could not be given as it severely hydrolyzed.

Key value for chemical safety assessment

Additional information