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Diss Factsheets
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EC number: 943-492-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
48-hour EC50 > 28 mg/L (no effects at limit of solubility), OECD 202, EU Method C.2, ISO 6341 and OECD 23, Migchielsen (2007)
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 28 mg/L
Additional information
The short term toxicity of the test material to the aquatic invertebrate, Daphnia magna, was investigated in a study which was conducted under GLP conditions and in accordance with the standardised guidelines OECD 202, EU Method C.2, ISO 6341 and OECD 23.
During the study twenty Daphnia per test group (4 vessels, 5 Daphnia per vessel) were exposed to a blank-control and a 0.45 µm filtered solution prepared at a loading rate of 100 mg/L. In addition, ten Daphnia per test group (2 vessels, 5 per vessel) were exposed to dilutions containing .0 and 10% of the filtrate. The total test period was 48 hours and samples for analyses of actual exposure concentrations were taken at the start and the end of the test period.
Analysis of the samples taken from the filtrate prepared at a loading rate of 100 mg/L showed that the measured concentration during the 48-hour test period remained stable at 28 mg/L. The low lithium background measured in samples from the blank-control originated from lithium traces present in the purified water used for preparation of the test medium and this did not affect the exposure of daphnia or the study integrity.
Under the conditions of the study the test material did not induce acute immobilisation of Daphnia magna at 28 mg/L, being the average concentration measured in a 0.45 µm filtered solution prepared at a loading rate of 100 mg/L (NOEC). The 48h-EC50 based on actual measured concentrations exceeded 28 mg/L, being the expected maximum soluble concentration in test medium.
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