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Registration Dossier
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EC number: 427-090-8 | CAS number: 116044-44-1
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation in aquatic species: fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
- Report date:
- 2015
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 305 (Bioaccumulation in Fish: Aqueous and Dietary Exposure) -I: Aqueous Exposure Bioconcentration Fish Test
Test material
Constituent 1
- Radiolabelling:
- yes
Test organisms
- Test organisms (species):
- Lepomis macrochirus
Study design
- Route of exposure:
- aqueous
- Test type:
- flow-through
- Water / sediment media type:
- natural water: freshwater
- Total exposure / uptake duration:
- 32 d
- Total depuration duration:
- 28 d
Results and discussion
Lipid contentopen allclose all
- Lipid content:
- ca. 3.9 %
- Time point:
- start of exposure
- Remarks on result:
- other:
- Lipid content:
- ca. 7.4 %
- Time point:
- end of exposure
- Remarks on result:
- other:
Bioaccumulation factoropen allclose all
- Conc. / dose:
- 2.1 µg/L
- Type:
- BCF
- Value:
- 240 L/kg
- Basis:
- normalised lipid fraction
- Calculation basis:
- steady state
- Remarks on result:
- other:
- Conc. / dose:
- 22 µg/L
- Type:
- BCF
- Value:
- 345 L/kg
- Basis:
- normalised lipid fraction
- Calculation basis:
- steady state
- Remarks on result:
- other:
- Conc. / dose:
- 1.7 µg/L
- Type:
- BCF
- Value:
- 318 L/kg
- Basis:
- normalised lipid fraction
- Calculation basis:
- steady state
- Remarks on result:
- other:
- Conc. / dose:
- 16 µg/L
- Type:
- BCF
- Value:
- 300 L/kg
- Basis:
- normalised lipid fraction
- Calculation basis:
- steady state
- Remarks on result:
- other:
- Conc. / dose:
- 2.1 µg/L
- Type:
- BCF
- Value:
- 240 L/kg
- Basis:
- normalised lipid fraction
- Calculation basis:
- kinetic
- Remarks on result:
- other:
- Conc. / dose:
- 22 µg/L
- Type:
- BCF
- Value:
- 345 L/kg
- Basis:
- normalised lipid fraction
- Calculation basis:
- kinetic
- Remarks on result:
- other:
- Key result
- Conc. / dose:
- 22 µg/L
- Type:
- BCF
- Value:
- 436 L/kg
- Basis:
- normalised lipid fraction
- Calculation basis:
- kinetic
- Remarks on result:
- other:
- Conc. / dose:
- 1.7 µg/L
- Type:
- BCF
- Value:
- 391 L/kg
- Basis:
- normalised lipid fraction
- Calculation basis:
- kinetic
- Remarks on result:
- other:
- Conc. / dose:
- 16 µg/L
- Type:
- BCF
- Value:
- 358 L/kg
- Basis:
- normalised lipid fraction
- Calculation basis:
- kinetic
- Remarks on result:
- other:
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
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