Registration Dossier

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The acute toxicity of the test substance, Vivaldie, on the respiration of activated sewage sludge was evaluated using a 3 -hour static test according to OECD Guideline 209. The substance was tested in final concentrations of 1, 3.16, 10, 31.6 and 100 mg/L. The oxygen consumption of these solutions was measured for approximately 10 minutes, with a chart recorder, after an aeration of 3 hours. The EC50 (concentration expected to cause 50% inhibition of the respiration rate) of the test substance and the reference substance was determined considering the oxygen consumption of the controls as 100%. As the validity criteria were met (the difference between the two controls was below 15% and the EC50 of 3,5-dichlorophenol was between 5 and 30 mg/L), the test was considered valid. The respiration rate of the test solution of highest concentration (100 mg/L) was equivalent to the respiration rate of the first control (i.e. these rates were within 15% of each other). Therefore, the oxygen consumption rate of the four other test solutions (1 to 31.6 mg/L) was not determined. The 3 hour EC50 value (mg/L) for vivaldie was determined to be > 100 mg/L. The test substance should be considered as non-toxic for the micro-organisms of a water treatment plant.

Key value for chemical safety assessment

EC50 for microorganisms:
100 mg/L

Additional information