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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
review article or handbook
Title:
RTECS NUMBER : CZ4280000
Year:
2012
Bibliographic source:
RTECS (Registry of Toxic Effects of Chemical Substances);

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other:
Principles of method if other than guideline:
The data is taken from RTECS
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
5-hydroxyisophthalic acid
EC Number:
210-565-7
EC Name:
5-hydroxyisophthalic acid
Cas Number:
618-83-7
Molecular formula:
C8H6O5
IUPAC Name:
5-hydroxybenzene-1,3-dicarboxylic acid
Details on test material:
Name of test material: 5-hydroxyisopthalic acid
Molecular formula:C8H6O5
Substance type: Organic

Test animals

Species:
mouse

Administration / exposure

Route of administration:
oral: unspecified
Doses:
6900 mg/kg

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
6 900 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
The LD50 value of 5-hydroxyisophthalic acid in mouse is 6900 mg/kg
Executive summary:

The LD50 value of 5-hydroxyisophthalic acid in mouse is 6900 mg/kg and hence it can be concluded that the chemical shall not exhibit toxicity by the oral route.