Registration Dossier
Registration Dossier
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EC number: 243-573-4 | CAS number: 20193-20-8
Endpoint summary
Administrative data
Description of key information
Acutely harmful to aquatic organisms.
The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations.
This acute aquatic toxicity assessment was based on the following data:
A GLP guideline study according to OECD 203 is available for the toxicity assessment of the test substance to fish. In this study, a 96 -h LC0 value of 1000 mg/L and a 96 -h LC50 > 1000 mg/L to zebra fish was determined. These values refer to the nominal values since the measured concentrations were within 10 % of the nominal concentrations (Hoechst, 1998). Therefore, the substance is considered as acutely not harmful to fish.
In a static test according to OECD guideline 202 (BASF AG, 1999) an EC50 of 54.3 mg/L for the mobility of Daphnia magna after a 48-hour exposure to the test substance was determined. This result was not pH dependent as was demonstrated by the use of neutralised samples of 50 and 100 mg/L.Therefore, the substance is considered acutely harmful to aquatic invertebrates.
No data on the toxicity of the test substance to algae are available. Therefore, data derived from a study using the structurally similar substance diethylamine (CAS 109 -89 -7). The 72h-ErC50 based on growth rate was determined to be 50.9 mg/L and the 72 -h ErC10 was 34.3 mg/L (NITE, 2000).
Therefore, the substance is considered acutely harmful to aquatic algae.
The EC20 value of the test item on activated sludge was found to greater than 1000 mg/L in a GLP guideline study according to OECD 209 (BASF AG, 2005). Thus, the inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations.
Additionally, a long-term assessment is available for Daphnia magna using the structurally similar substance diethylamine (CAS 109-89-7; NITE, 2000). The chronic data were: EC10 for Daphnia= 4.07 mg/L and an ErC10 for algae of 34.3 mg/L. Therefore, the EC10 for aquatic invertebrates is used for PNEC derivation.
Additional information
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