Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin sensitisation
Remarks:
other: read across
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Title:
No information
Author:
Anonymous
Year:
2013
Bibliographic source:
OECD Toolbox v3.1

Materials and methods

Test guideline
Guideline:
other: read across (classification proteinbinding alerts for skin sensitisation by Oasis v1.1)
GLP compliance:
no
Type of study:
other: read across

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2-dimethoxy-1,2-diphenylethan-1-one
EC Number:
246-386-6
EC Name:
2,2-dimethoxy-1,2-diphenylethan-1-one
Cas Number:
24650-42-8
Molecular formula:
C16H16O3
IUPAC Name:
2,2-dimethoxy-1,2-diphenylethan-1-one

Results and discussion

In vivo (non-LLNA)

Results
Reading:
other: skin sensitisation score
Group:
test chemical
Dose level:
0
No. with + reactions:
0
Total no. in group:
0
Clinical observations:
The study scores negative with 60% certainty
Remarks on result:
other: Reading: other: skin sensitisation score. Group: test group. Dose level: 0. No with. + reactions: 0.0. Total no. in groups: 0.0. Clinical observations: The study scores negative with 60% certainty.

Applicant's summary and conclusion

Interpretation of results:
not sensitising
Remarks:
Migrated information Criteria used for interpretation of results: EU