Registration Dossier
Registration Dossier
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EC number: 695-745-7 | CAS number: 1079221-49-0
Auto flammability
Administrative data
- Endpoint:
- relative self-ignition temperature (solids)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From September 27, 2010 to September 28, 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP study conducted in compliance with international guidelines.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 014
- Report date:
- 2014
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.16 (Relative Self-Ignition Temperature for Solids)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2-({3-aminopyrazolo[1,5-a]pyridin-2-yl}oxy)ethan-1-ol hydrochloride
- EC Number:
- 695-745-7
- Cas Number:
- 1079221-49-0
- Molecular formula:
- C9 H11 N3 O2, ClH
- IUPAC Name:
- 2-({3-aminopyrazolo[1,5-a]pyridin-2-yl}oxy)ethan-1-ol hydrochloride
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
Constituent 1
Results and discussion
Relative self-ignition temperature (solids)
- Remarks on result:
- other: Test item started melting under decomposition at about 220 °C (see report C77426). Test item showed no relevant exothermic reaction between room temperature and 220 °C.
- Remarks:
- at atm. press. of 92.2 kPa
Any other information on results incl. tables
Test item showed no relevant exothermic reaction between room temperature and 220 °C, but a clear exothermic heat effect could be observed at an oven temperature at about 380 °C. As the above-mentioned guideline only applies to solids, the temperature range between 220 °C and 400 °C is not relevant for the present test item.
Applicant's summary and conclusion
- Executive summary:
During this study, the self-ignition temperature was determined according to Council Regulation (EC) No. 440/2008,, Part A, Methods for the determination of physico-chemical properties, A.16 “Relative self-ignition temperature for solids".
Therefore, the test item was filled into a cube and heated in an oven. The temperatures of the oven and the sample were continuously recorded while the temperature of the oven was increased to approximately 400 °C. Test item started melting under decomposition at about 220 °C (see Harlan Laboratories study C77426). Test item showed no relevant exothermic reaction between room temperature and 220°C.
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