1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, hydrochloride (1:2), (2S)-

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2014

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Deviations:

no

GLP compliance:

yes

Type of method:

other: Differential Thermal Analysis (DTA)/Differential Scanning Calorimetry (DSC)

Melting / freezing pt.:

218 - 227 °C

Decomposition:

yes

Decomp. temp.:

> 227

Remarks on result:

other: No pressure reported

The melting point is not reversible and the colour of the substance changed after this temperature which indicates that the product could start to decompose at this temperature.

Conclusions:

The melting point of 1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, dihydrochloride, (2S)- was found to be between 218 and 227 °C.

Executive summary:

The melting point of1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, dihydrochloride, (2S)- was tested according to OECD Guideline 102 in a DTA/DSC system with a heating rate of 1 K/min in crucible made of aluminium with perforated lid and no pressure was reported. The melting point of 1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, dihydrochloride, (2S)- was found to be between 218 and 227 °C. The melting point was not reversible and the colour of the substance changed after this temperature which indicates that the product could start to decompose at this temperature.

Description of key information

The melting point of 1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, dihydrochloride, (2S)- was found to be between 218 and 227 °C.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:

222.5 °C

Additional information

The melting point is not reversible and the colour of 1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, dihydrochloride, (2S)- changed after this temperature which indicates that 1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, dihydrochloride, (2S)- could start to decompose at this temperature.