Registration Dossier
Registration Dossier
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EC number: 671-709-6 | CAS number: 430-67-1
Toxicity to microorganisms
Administrative data
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP study according to EU/OECD guideline.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 011
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.11 (Biodegradation: Activated Sludge Respiration Inhibition Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2,2-difluoroethan-1-amine
- EC Number:
- 671-709-6
- Cas Number:
- 430-67-1
- Molecular formula:
- C2H5F2N
- IUPAC Name:
- 2,2-difluoroethan-1-amine
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- activated sludge of a predominantly domestic sewage
Study design
- Test type:
- flow-through
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 3 h
Results and discussion
Effect concentrations
- Duration:
- 3 h
- Dose descriptor:
- EC50
- Effect conc.:
- 916.8 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
- Details on results:
- The test item showed 54.6 % respiration inhibition of activated sludge at a test item concentration of 1000 mg/L.
Applicant's summary and conclusion
- Conclusions:
- The test item showed 54.6 % respiration inhibition of activated sludge at a test item concentration of 1000 mg/L.
The EC50 is 916.8 mg/L.
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