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EC number: 226-242-9 | CAS number: 5333-42-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- August 25 to September 5, 2009
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC estimation method
- Media:
- soil/sewage sludge
Test material
- Details on test material:
- - Name of test material (as cited in study report): 2-Octyldodecan-1-ol
- Substance type: pur active substance
- Physical state: liquid
- Lot/batch No.: 03508
- Expiration date of the lot/batch: January 1, 2011
- Storage condition of test material: room temperature, protected from moisture and light
Constituent 1
- Radiolabelling:
- no
Study design
- Test temperature:
- Column temperature: 20 °C
Temperature (RI): 30 °C
HPLC method
- Details on study design: HPLC method:
- EQUIPMENT
- Apparatus: HPLC
- Type: Waters 616 with autosampler Waters 717 plus
- Type, material and dimension of analytical (guard) column: YMC-Pack Cyano, cyanopropyl solid phase, 250 x 4.0 mm, YMC Europe GmbH
- Detection system: 2996 Diode Array Detector (DAD), Waters, for the reference items and IR detector HP 1047 A, Hewlett Packard, for the test item
MOBILE PHASES
- Type: 70:30 (% v/v) acetonritrile : HPLC water
- Experiments with additives carried out on separate columns: no
- Solutes for dissolving test and reference substances: acteonitril/water for test substance, methanol for reference substances
DETERMINATION OF DEAD TIME
- Method: by inert substances which are not retained by the column: NaNO3
REFERENCE SUBSTANCES
- Identity:
Acetanilide (CAS 103-84-4), Atrazine (CAS 1912-24-9), Monuron (CAS 150-68-5), 2,5-Dichloroaniline (CAS 95-82-9), Benzoic acid phenylester (CAS 93-99-2), Fenthion (CAS 55-38-9), Phenanthrene (CAS 85-01-8), 4,4¿-DDT (CAS 50-29-3)
DETERMINATION OF RETENTION TIMES
- Quantity of test substance introduced in the column: 100 µl of 400 mg/l solution
- Quantity of reference substances: 100 µl of 100 mg/l solution
- Intervals of calibration: each reference item was analysed separately before and after analysis of the test item
REPETITIONS
- Number of determinations: 3
EVALUATION
- Calculation of capacity factors k': k'= (retention time tR - dead time t0)/dead time t0
- Determination of the log Koc value: By means of the adsorption coefficient values (Koc) and the corresponding capacity factors of the reference items a calibration calibration graph of log k` vs. log Koc,soil and log k ' versus logKoc, sewage sludge was plotted. The Koc values of the test item was then calculated based on the calibration curves.
Results and discussion
Adsorption coefficientopen allclose all
- Key result
- Type:
- Koc
- Value:
- ca. 840 000 000
- Key result
- Type:
- log Koc
- Value:
- ca. 8.92
Results: HPLC method
- Details on results (HPLC method):
- - Retention times of reference substances used for calibration [min]:
Acetanilide: 3.333
Atrazine: 3.396
Monuron: 3.428
2,5-Dichloroaniline: 3.476
Benzoic acid phenylester: 3.513
Fenthion: 3.558
Phenanthrene: 3.669
4,4'-DDT: 3.847
- Details of fitted regression line (log k' vs. log Koc): For soil the slope of the regression line were determined 0.0282 with an intercept of -0.0892. For sewage sludge the slope of the regression line were determined 0.0256 with an intercept of -0.0876.
- Average retention data for test substance [min]: 4.354
Any other information on results incl. tables
log Koc, soil = 8.92, Koc, soil=8.4x10exp8
log Koc, sewage sludge = 9.79, Koc, sewage sludge=6.2x10exp9.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- For 2-Octyldodecanol for soil the log Koc was determined to be 8.92 with a corresponding KOC value of 8.4x10exp8. For sewage sludge the log Koc was determined to be 9.79 with a corresponding Koc of 6.2x10exp9.
- Executive summary:
At test conditions the retention time of the test substance 2 -Octyldodecan-1 -ol was found to be higher as the retention time of the reference item 4,4-DDT (highest Koc value in the set). Therefore the log Koc values were extrapolated.
For 2-Octyldodecanol for soil the log Koc was determined to be 8.92 with a corresponding KOC value of 8.4x10exp8. For sewage sludge the log Koc was determined to be 9.79 with a corresponding Koc of 6.2x10exp9.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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