Registration Dossier
Registration Dossier
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EC number: 687-535-9 | CAS number: 122586-52-1
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline study, GLP compliance
Data source
Reference
- Reference Type:
- other: inquiry result from ECHA
- Title:
- Unnamed
- Year:
- 2 011
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 401 (1987)
- GLP compliance:
- yes
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- bis[2,2,6,6-tetramethyl-1-(octyloxy)piperidin-4-yl] decanedioate
- EC Number:
- 687-535-9
- Cas Number:
- 122586-52-1
- Molecular formula:
- C44H84N2O6
- IUPAC Name:
- bis[2,2,6,6-tetramethyl-1-(octyloxy)piperidin-4-yl] decanedioate
Constituent 1
Test animals
- Species:
- other: rat, TIf:RAlf (SPF)
Administration / exposure
- Vehicle:
- other: Distilled water containing 0.5% carboxymethylcellulose and 0.1 %polysorbate 80.
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Mortality:
- Male: 2000 mg/kg bw; Numberof animals: 5; Numberof deaths: 0
Female: 2000 mg/kg bw; Numberof animals: 5; Numberof deaths: 0 - Clinical signs:
- Signsof toxicity related to dose levels:
Unspecific symptoms of intoxication: piloerection, hunched
posture. exophthalmus and dyspnoea. - Gross pathology:
- Effectson organs: no effects
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
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