Registration Dossier
Registration Dossier
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EC number: 601-350-2 | CAS number: 115241-16-2
Endpoint summary
Administrative data
Description of key information
No skin and eye irritation toxicity studies are available for N-Formylaminosorbose. However, there is a skin and eye irritation toxicity study for the structural analogue N-Formylaminosorbit (CAS 89182-60-5):
Skin irritation in vivo (Rabbit-NZW, GLP, OECD TG 404): not irritating to the skin
[Bayer AG, Report No. PH-18456, 1989-10-23]
Eye irritation in vivo (Rabbit-NZW, GLP, OECD TG 405): not irritating to the eye
[Bayer AG, Report No. PH-18456, 1989-10-23]
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
No skin and eye irritation toxicity studies are available for N-Formylaminosorbose. However, there is a skin and eye irritation toxicity study for the structural analogue N-Formylaminosorbit (CAS 89182-60-5):
In the skin irritation test in all 3 animals no signs of skin irritation could be observed.
In the eye irritation test discharge (grade 1) 1 h after instillation was the only finding in all 3 animals. No signs of eye irritation could be observed after 24, 48 and 72 h.
Justification for classification or non-classification
Based on the study results a classification according to Directive 67/548/EEC and Regulation (EC) No. 1272/2008 (CLP) is not required.
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