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Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report date:
2015

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Test type:
acute toxic class method
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
2-{phenyl[2-(tetradecanoyloxy)phenyl]methyl}phenyl tetradecanoate
EC Number:
941-526-9
Molecular formula:
C47H68O4
IUPAC Name:
2-{phenyl[2-(tetradecanoyloxy)phenyl]methyl}phenyl tetradecanoate

Test animals

Species:
rat
Strain:
Wistar
Sex:
female
Details on test animals or test system and environmental conditions:
Test animals: Crl:WI (Charles River Deutschland)

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
corn oil
Doses:
2000 mg/kg
No. of animals per sex per dose:
2 x 3 rats
Control animals:
no

Results and discussion

Effect levels
Sex:
female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Mortality:
none
Clinical signs:
other: All rats were free of any abnormalities.
Gross pathology:
No pathological signs observed

Applicant's summary and conclusion

Conclusions:
The oral LD50 is >2000 mg/kg b.w. - "Category 5" or "Not classified"