Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
oxidising solids
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Study period:
Study Test Phase 2014-01-30 to 2014-02-25. Report complete 2014-04-15.
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: As the study is an estimation by calculation rather than a full experimental study it is considered to meet the criteria for classification as reliable with restrictions according to Klimisch et al (1997).

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2014
Report date:
2014

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.17 (Oxidising Properties (Solids))
Deviations:
no
Principles of method if other than guideline:
Under COLUMN 2 “SPECIFIC RULES FOR ADAPTATION FROM COLUMN 1” in the REGULATION (EC) No 1907/2006 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL of 18 December 2006, it states The study does not need to be conducted if: “the substance is incapable of reacting exothermically with combustible materials, for example on the basis of the chemical structure” accordingly “The structure of the test material was assessed for chemical groups that would imply oxidising properties. Examples of such groups are nitrates, metal oxides, hypofluorites, difluoroaminopolynitroaryls, perchlorates, bromates and iodites.”


The oxidising properties were predicted using Method A17 Oxidising Properties (Solids) of Commission Regulation (EC) No 440/2008 of 30 May 2008.

Based on the chemical structure the result for the oxidising properties has been predicted negative.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
lithium hydrogen 7-{(E)-[2-amino-4-(2-naphthyl)-1,3-thiazol-5-yl]diazenyl}naphthalene-1,3,5-trisulfonate (2:1:1)
EC Number:
940-433-0
Molecular formula:
C23H14Li2N4O9S4
IUPAC Name:
lithium hydrogen 7-{(E)-[2-amino-4-(2-naphthyl)-1,3-thiazol-5-yl]diazenyl}naphthalene-1,3,5-trisulfonate (2:1:1)
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder

Results and discussion

Test results (Oxidising solids)
Key result
Sample tested:
other: Theoretical assessment
Parameter:
other: Predicted negative based on the chemical structure
Result:
ca. 0 - ca. 0 other: theoretical assessment
Remarks on result:
other: There are no structural alerts within the chemical structure of the test item that would indicate oxidising properties

Any other information on results incl. tables

There are no structural alerts within the chemical structure of the test item. Based on the chemical structure of the test item, the result for the oxidizing properties has been predicted negative.

Please see background material for the chemical structure.

Applicant's summary and conclusion

Interpretation of results:
other: no oxidising properties
Remarks:
Migrated information based on the chemical structure
Conclusions:
There are no structural alerts within the chemical structure of the test item. Based on the chemical structure of the test item, the result for the oxidizing properties has been predicted negative.
Executive summary:

Introduction

The prediction was undertaken using a procedure designed to be compatible with Method A17 Oxidising Properties (Solids) of Commission Regulation (EC) No 440/2008 of 30 May 2008.

The structure of the test item was assessed for chemical groups that would imply oxidizing properties. Examples of such groups are nitrates, metal oxides, hypofluorites, difluoroaminopolynitroaryls, perchlorates, bromates and iodites.

 

Full structural details are given in Bretherick’s Handbook of Reactive Chemical Hazards, 4th Edition, Butterworths, London, 1990.

If there are no structural alerts within the structure, then the oxidizing properties can be predicted negative.

Results & Conclusions

There are no structural alerts within the chemical structure of the test item. Based on the chemical structure of the test item, the result for the oxidizing properties has been predicted negative.