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Toxicological information

Genetic toxicity: in vitro

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Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Type of information:
experimental study
Adequacy of study:
key study

Data source

Reference
Reference Type:
other:
Title:
Unnamed
Report date:
1992

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method B.13/14 (Mutagenicity - Reverse Mutation Test Using Bacteria)

Test material

Method

Species / strain
Species / strain / cell type:
bacteria, other:
Additional strain / cell type characteristics:
not specified

Results and discussion

Test resultsopen allclose all
Species / strain:
bacteria, other:
Metabolic activation:
with and without
Genotoxicity:
other:
Cytotoxicity / choice of top concentrations:
cytotoxicity
Vehicle controls validity:
other:
Untreated negative controls validity:
other:
Positive controls validity:
other:
Species / strain:
bacteria, other:
Metabolic activation:
with and without
Genotoxicity:
negative
Cytotoxicity / choice of top concentrations:
cytotoxicity
Vehicle controls validity:
other:
Untreated negative controls validity:
other:
Positive controls validity:
other:

Applicant's summary and conclusion

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