6-(2-chloro-6-cyano-4-nitrophenylazo)-4-methoxy-3-[N-(methoxycarbonylmethyl)-N-(1-methoxycarbonylethyl)amino]acetanilide

Basic toxicokinetics

Administrative data

Endpoint:

basic toxicokinetics

Type of information:

other: Expert assessment

Adequacy of study:

key study

Study period:

The study was conducted on 03 September 2015

Cross-reference

Reason / purpose for cross-reference:

reference to same study

Data source

Reference

Reference Type:

other: Expert assessment

Title:

Unnamed

Year:

2015

Report date:

2015

Materials and methods

Principles of method if other than guideline:

A paper-based toxicokinetic assessment has been conducted for this substance.

Test material

Test material information

Constituent 1

Reference substance name:

-

EC Number:

430-500-8

EC Name:

-

Cas Number:

204277-61-2

Molecular formula:

Hill formula: C23 H23 Cl N6 O8 CAS formula: C23 H23 Cl N6 O8

IUPAC Name:

methyl 2-({4-[2-(2-chloro-6-cyano-4-nitrophenyl)diazen-1-yl]-5-acetamido-2-methoxyphenyl}(2-methoxy-2-oxoethyl)amino)propanoate

Results and discussion

Any other information on results incl. tables

A paper-based toxicokinetic assessment has been conducted for this substance. Available studies were reviewed by a qualified toxicologist. The assessment of the likely toxicokinetic behaviour of the test item was provided to the extent that can be derived from the relevant available information at the time of the assessment. The available information indicates absorption of the test substance following oral administration takes place via the gastrintestina tract. Once absorbed, the substance may be distributed in the serum and the significant route of excretion via the faeces. there is no evidence suggesting that the test substance may be metabolised, however no studies have been conducted to identify metabolites.

Applicant's summary and conclusion

Executive summary:

A paper-based toxicokinetic assessment has been conducted for this substance. Available studies were reviewed by a qualified toxicologist. The assessment of the likely toxicokinetic behaviour of the test item was provided to the extent that can be derived from the relevant available information at the time of the assessment. The available information suggests indicates absorption of the test substance following oral administration takes place via the gastrintestinal tract. Once absorbed, the substance may be distributed in the serum and the significant route of excretion via the faeces. there is no evidence suggesting that the test substance may be metabolised, however no studies have been conducted to identify metabolites.