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EC number: 205-861-8 | CAS number: 156-62-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- transformation / dissolution of metals and inorganic metal compounds
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 2019-02-22
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: OECD Series on Testing and Assessment No. 29: Guidance document on transformation/dissolution of metals and metal compounds in aqueous media
- Version / remarks:
- 23 July 2001
- Principles of method if other than guideline:
- The test substance was dispersed in water to get a 10% aqueous suspension. Filled in a bottle this suspension was agitated on a shaker for defined times at ambient conditions. For each sampling date a separate bottle was prepared. At each sampling date the suspension was filtrated and the filtrate was analyzed for cyanamide, dicyandiamide, calcium and pH-value. The total period of the test was 28 days with 8 sampling dates (1, 2, 3, 4, 7, 14, 21 and 28 days).
- GLP compliance:
- no
- Type of method:
- flask method
- Specific details on test material used for the study:
- Calcium cyanamide technical grade
- Key result
- Type of test:
- other: Transformation of calcium cyanamide to hydrogen cyanamide
- Mean dissolved conc.:
- >= 7.76 - <= 35.3 g/L
- Element analysed:
- Cyanamide
- Loading of aqueous phase:
- 100 g/L
- Incubation duration:
- 28 d
- Test conditions:
- in Water at 18 - 24°C; loading with calcium cyanamide technical grade
- Key result
- Type of test:
- other: Transformation of calcium cyanamide to hydrogen cyanamide
- Mean dissolved conc.:
- >= 2.49 - <= 20.5 g/L
- Element analysed:
- Cyanoguanidine (Dicyandiamide)
- Loading of aqueous phase:
- 100 g/L
- Incubation duration:
- 28 d
- Test conditions:
- in Water at 18 - 24°C; loading with calcium cyanamide technical grade
- Key result
- Type of test:
- other: Transformation of calcium cyanamide to hydrogen cyanamide
- Mean dissolved conc.:
- >= 4.6 - <= 16.9 g/L
- Element analysed:
- Calcium
- Loading of aqueous phase:
- 100 g/L
- Incubation duration:
- 28 d
- Test conditions:
- in Water at 18 - 24°C; loading with calcium cyanamide technical grade
- Details on results:
- Table 1 shows the results of the different sampling dates from day 1 to day 28. Listed are the concentrations of cyanamide, dicyandiamide, calcium and the pH-value of the filtrate. Further species as result of side- or secondary reactions (such as urea, ammonia, N-cyanourea) have not been analysed.
The analysis results show, that cyanamide and dicyandiamide formed thereof are the main dissolved species formed from calcium cyanamide technical grade in contact with water. Side reactions of both species, forming urea, ammonia and others (not quantitatively determined in this study) account for the decrease of the sum of cyanamide and dicyandiamide.
Based on an initial calcium cyanamide content of 67.7% in the test item, only approx. 20% are still present after 28 days as cyanamide. As expected, the majority is dimerized to dicyandiamide.
The pH value of the filtrate remains almost constant at approx. 12 over the whole period of the test.
The calcium concentration fluctuates in the first week between 11 and 17 g/L, and decreased continuously to 4.6 g/L in the next 3 weeks. The reason has not been investigated, but it is probably the effect on solubility of calcium ions of hydrogen cyanamide, dicyandiamide and the other substances generated. - Conclusions:
- The analysis results show, that cyanamide and dicyandiamide formed thereof are the main dissolved species formed from calcium cyanamide technical grade in contact with water. Based on an initial calcium cyanamide content of 67.7% in the test item, only approx. 20% are still present after 28 days as cyanamide. As expected, the majority is dimerized to dicyandiamide.
- Executive summary:
The intention of the test was to determine the solubility of calcium cyanamide technical grade in aqueous media. Due to the fact that calcium cyanamide reacts immediately with water, a determination of water solubility of the substance in its proper definition is not possible.
The test substance was dispersed in water to get a 10% aqueous suspension. Filled in a bottle this suspension was agitated on a shaker for defined times at ambient conditions. For each sampling date a separate bottle was prepared. At each sampling date the suspension was filtrated and the filtrate was analyzed for cyanamide, dicyandiamide, calcium and pH-value. The total period of the test was 28 days with 8 sampling dates (1, 2, 3, 4, 7, 14, 21 and 28 days).
The analysis results show, that cyanamide and dicyandiamide formed thereof are the main dissolved species formed from calcium cyanamide technical grade in contact with water. Side reactions of both species, forming urea, ammonia and others (not quantitatively determined in this study) account for the decrease of the sum of cyanamide and dicyandiamide.
Based on an initial calcium cyanamide content of 67.7% in the test item, only approx. 20% are still present after 28 days as cyanamide. As expected, the majority is dimerized to dicyandiamide.
The pH value of the filtrate remains almost constant at approx. 12 over the whole period of the test.
The calcium concentration fluctuates in the first week between 11 and 17 g/L, and decreased continuously to 4.6 g/L in the next 3 weeks. The reason has not been investigated, but it is probably the effect on solubility of calcium ions of hydrogen cyanamide, dicyandiamide and the other substances generated.
- Endpoint:
- water solubility
- Data waiving:
- study technically not feasible
- Justification for data waiving:
- other:
Referenceopen allclose all
Table 1: Results for the transformation of test item calcium cyanamide technical grade in aqueous media as a function of time
Sampling date [days] |
Cyanamide [g/L] |
Dicyandiamide [g/L] |
Calcium [g/L] |
pH-value |
1 |
35.3 |
2.49 |
12.8 |
12.2 |
2 |
32.2 |
4.96 |
16.9 |
12.1 |
3 |
29.1 |
7.32 |
14.9 |
12.1 |
4 |
26.5 |
9.17 |
14.1 |
12.2 |
7 |
21.8 |
12.9 |
11.4 |
12.1 |
14 |
15.0 |
17.0 |
7.4 |
12.2 |
21 |
11.0 |
19.3 |
6.0 |
12.3 |
28 |
7.76 |
20.5 |
4.6 |
12.4 |
Description of key information
Upon dissolution in water calcium cyanamide technical grade is transformed to (hydrogen) cyanamide. Therefore, it is technically not possible to determine the water solubility of calcium cyanamide technical grade itself.
Key value for chemical safety assessment
Additional information
A test was conducted to further investigate the dissolution behaviour of calcium cyanamide technical grade in water. A 10% aqueous suspension of the test item was prepared, and samples were taken after defined time points for up to 28 days. At each sampling, the test suspension was filtrated, and the filtrate was analysed for cyanamide, dicyandiamide, calcium and pH-value.
The analysis results show, that cyanamide and dicyandiamide formed thereof are the main dissolved species formed from calcium cyanamide technical grade in contact with water. Side reactions of both species, forming urea, ammonia and others (not quantitatively determined in this study) account for the decrease of the sum of cyanamide and dicyandiamide.
Based on an initial calcium cyanamide content of 67.7% in calcium cyanamide technical grade, only approx. 20% are still present after 28 days as cyanamide. As expected, the majority is dimerized to dicyandiamide.
The pH value of the filtrate remains almost constant at about 12.5 over the whole period of the test.
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