Registration Dossier
Registration Dossier
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EC number: 241-029-0 | CAS number: 16958-92-2
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
No toxic effects up to the limit of water solubility for Cyprinodon variegatus (OECD 203)
Key value for chemical safety assessment
Additional information
One study investigating the toxicity of Bis(tridecyl) adipate (CAS 16958-92-2) to saltwater fish is available. The study was conducted under static conditions according to OECD guideline 203 using Cyprinodon variegatus as test organism (BenKinney, 1986). The test material was directly added to the test vessels preparing oil-water suspensions (OWD) in a range of 500 to 5000 mg/L. Undissolved test material was not removed, which bears the problem that observed effects could be related to physical interferences rather than systemic toxicity. There is no scientific basis to define a cut off limit value for solubility below which no toxicity could occur. There may be technical difficulties to perform the test, e.g. sensitivity of the analytical method used for the determination of test concentration. Tests above the limit of solubility should not be interpreted as pelagic toxicity, but as confounded by physical effects. However, this is considered negligible for this study, because the relevant effect value (EC50) after a 96 h test period is determined to be above the highest test concentration of 5000 mg/L.
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