Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-404-7 | CAS number: 106-50-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Guidance on Safe Use
Administrative data
First-aid measures
Symptoms and effects: Irritating to eyes. skin absorption. May cause sensitization by skin contact. Toxic by inhalation, in contact with
skin and if swallowed.
First aid:
General
In case of accident or if you feel unwell, seek medical advice immediately (show the label where
possible).
Inhalation
Move to fresh air, rest, half upright position, loosen clothing. Oxygen or artificial respiration if there is
difficulty in breathing. Seek medical advice after significant exposure.
Skin
Wash immediately with soap and water. Take off contaminated clothing immediately. In case of skin
eruption seek medical advice.
Eye
Rinse thoroughly with plenty of water. Eyelids should be held away from the eyeball to ensure thorough
rinsing. Always seek medical attention.
Ingestion
Rinse mouth, give water to drink. Do NOT induce vomiting. Always seek medical attention.
Advice to physician
Do not delay treatment of exposed individuals, death may result.
Fire-fighting measures
5. FIRE-FIGHTING MEASURES
Extinguishing media
waterjet, dry chemical powder, Carbon dioxide, foam
Unsuitable extinguishing media
none known.
Hazardous decomposition / combustion products
Fire will produce dense black acrid smoke .
Protective equipment
Wear self contained breathing apparatus.
Other information
Water used to extinguish a fire should not be allowed to enter the drainage system or water courses.
Fire and explosion hazard
Do not inhale explosion or combustion vapours.
Accidental release measures
6. ACCIDENTAL RELEASE MEASURES
Personal precautions
Avoid contact with skin. For personal protection see Section 8.
Environmental precautions
This material and its container must be disposed of as hazardous waste.
Methods for cleaning up
Collect as much as possible in a clean container for (preferable) reuse or disposal.
Handling and storage
7. HANDLING AND STORAGE
Handling
Persons with a history of skin sensitization problems should not be employed in any process in which this
product is used.
Ensure good ventilation and local exhaustion of the working area.
Fire and explosion prevention
Keep away from sources of ignition - No smoking.
Storage requirements
Keep container tightly closed. Do not store together with oxidants.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 1673
Shippingopen allclose all
SpecialProvisionsopen allclose all
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- 1673
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- 1673
Shipping information
- Proper shipping name and description:
- Phenylenediamines (o-, m-, p-)
- Chemical name:
- 1,4-Phenylenediamine
- Labels:
- 6.1 + P
- Marine pollutant
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- UN number
1673
Class
6.1
Packing group
III
Proper Shipping Name
Phenylenediamines (o-, m-, p-)
Shipping information
- Proper shipping name and description:
- Phenylenediamines (o-, m-, p-)
- Chemical name:
- 1,4-Phenylenediamine
- Labels:
- 6.1
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Guidance on safe use
Human Health - Workers
Safe uses can only be guaranteed for working conditions as mentioned in the exposure in Chapter 10, in combination with the Risk management Measures mentioned in the table below.
Exposure Scenario 1: Manufacture and use as an intermediate
Process Category Exposure time Concentration Risk Management Measures to be used
Proc1: Non-contact plant. Manufacture and use.
Outside. (vapour pressure liquid 4000 Pa) > 4 hours 100% Tested chemical resistant gloves (EN374)
Proc1: Transport. Outside.
(vapour pressure liquid 4000 Pa) > 4 hours 100% Tested chemical resistant gloves (EN374)
Proc2: Sampling (solid low dust). Outside. > 4 hours 100% Tested chemical resistant gloves (EN374) plus basic
training ‘how to use gloves’
PROC8b: Transfer of substance or preparation
(charging/discharging) from/to vessels/large
containers at dedicated facilities 15 min. – 1 hr. 100% Tested chemical resistant gloves (EN374), with intensive
management supervision controls.
Full face respirator (EN140) with type A filter or better
Local Exhaust Ventilation (LEV) (90% efficiency)
Proc15: Laboratory activities (solid low dust).
Inside. > 4 hours 100% Tested chemical resistant gloves (EN374)
Proc15: Laboratory activities (solution;
vapour pressure PPD: 0.01 Pa). Inside. < 4 hour >25% Tested chemical resistant gloves (EN374)
> 4 hours >25% Tested chemical resistant gloves (EN374)
Exposure Scenario 2: Use as an intermediate
Process Category Exposure time Concentration Risk Management Measures to be used
Proc1: Use as an intermediate plus transfer
(closed systems). Inside. (vapour pressure
liquid 4000Pa) > 4 hours 100% Tested chemical resistant gloves (EN374)
Proc15: Laboratory activities (solid low dust).
Inside. > 4 hours 100% Tested chemical resistant gloves (EN374)
Proc15: Laboratory activities (solution; vapour
pressure PPD: 0.01 Pa). Inside. < 4 hour >25% Tested chemical resistant gloves (EN374)
> 4 hours >25% Tested chemical resistant gloves (EN374)
Stability and reactivity
Conditions to avoid
Avoid reaction with the following materials: oxidising agents.
Stability
Stable under recommended storage and handling conditions (see section 7).
Incompatibles
Corrosive to metals.
Hazardous decomposition products
nitrous gases (NOx).
Disposal considerations
Product: According to local regulations.
Contaminated packaging: According to local regulations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.