Registration Dossier
Registration Dossier
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EC number: 266-944-2 | CAS number: 67701-26-2 This substance is identified by SDA Substance Name: C12-C18 trialkyl glyceride and SDA Reporting Number: 16-001-00.
Direct observations: clinical cases, poisoning incidents and other
Administrative data
- Endpoint:
- direct observations: clinical cases, poisoning incidents and other
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only short abstract available.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 976
- Report date:
- 1976
Materials and methods
- Study type:
- study with volunteers
- Endpoint addressed:
- skin irritation / corrosion
- Principles of method if other than guideline:
- Patch Test in humans.
- GLP compliance:
- no
Test material
- Reference substance name:
- Glycerides, C12-18
- EC Number:
- 266-944-2
- EC Name:
- Glycerides, C12-18
- Cas Number:
- 67701-26-2
- Molecular formula:
- C39H74O6 to C57H110O6
- IUPAC Name:
- Glycerides, C12-18
- Details on test material:
- - Name of test material (as cited in study report): only trade name given
- Analytical purity: no data
Constituent 1
Method
- Type of population:
- not specified
- Subjects:
- - Number of subjects exposed: 5
- Ethical approval:
- not specified
- Route of exposure:
- dermal
- Reason of exposure:
- intentional
- Exposure assessment:
- not specified
- Details on exposure:
- Small quantities (not further specified) of the test substance as 50% solution in olive oil were applied by means of test plasters on the upper arms of a group of 5 test subjects, held in place for 24 h.
Results and discussion
- Clinical signs:
- During the 24 h exposure, none of the test subjects reported any discomfort. After patch removal and after a further 24 h, no visible skin changes were observed.
Applicant's summary and conclusion
- Conclusions:
- not irritating
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