Registration Dossier
Registration Dossier
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EC number: 422-630-9 | CAS number: 22208-25-9
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
- GLP compliance:
- yes
- Transformation products:
- not specified
- pH:
- 4
- Temp.:
- 25 °C
- DT50:
- > 8 760 h
- Type:
- not specified
- Key result
- pH:
- 7
- Temp.:
- 25 °C
- DT50:
- 158 h
- Type:
- not specified
- pH:
- 9
- Temp.:
- 25 °C
- DT50:
- < 24 h
- Type:
- not specified
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The test substance was hidrolytically stable at pH4, at pH7 the half-time was calculated to be 158h and at pH9 the substance was hydrolytically unstable.
- Executive summary:
The hydrolysis study was determined according to the EU Method C.7 (GLP study). Results show that the test substance was hydrolytically stable at pH4, at pH7 the half-time was calculated to be 158h and at pH9 the substance was hydrolytically unstable.
Reference
At ph4, the test item is hydrolytically stable. At pH7, the half-life times are 4.67 h (70 °C) and 2.42 h (80 °C). From these values the half-life time at 25 °C was calculated to be 158 h. At pH9 the test item is hydrolytically unstable (half-life time at 25 °C <1 day).
Description of key information
Key study. EU Method C.7 (GLP study). The results indicated that the test substance was hydrolytically stable at pH4, at pH7 the half-time was calculated to be 158h and at pH9 the substance was hydrolytically unstable.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 158 h
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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