Registration Dossier
Registration Dossier
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EC number: 422-630-9 | CAS number: 22208-25-9
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms, other
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.11 (Biodegradation: Activated Sludge Respiration Inhibition Test)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- GLP compliance:
- yes
- Analytical monitoring:
- not specified
- Test type:
- other: aerobic
- Total exposure duration:
- 0.5 h
- Key result
- Duration:
- 0.5 h
- Dose descriptor:
- IC50
- Effect conc.:
- > 284 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- not specified
- Duration:
- 0.5 h
- Dose descriptor:
- NOEC
- Effect conc.:
- > 284 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- not specified
- Details on results:
- The test substance had no inhibitory effect on the respiration rate of activated sludge at the duplicate measurements of 100 and 284 mg/l. Therefore, no further testing was needed.
- Conclusions:
- The EC50 was determined to be higher than 284 mg/L.
- Executive summary:
The study was conducted according to OECD No. 209 and EU Method C.11 (Activated sludged, respiratory inhibitory test) (GLP study).
The results shows that no inhibitory effect on respiration rate of activated sludges was observed. Hence, the EC50 for the substance was determined to be higher than 284 mg/L.
Reference
Description of key information
Toxicity to microorganisms (activated sludge): NOEC > 284 mg/L.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 284 mg/L
- EC10 or NOEC for microorganisms:
- 284 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
