Registration Dossier
Registration Dossier
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EC number: 424-090-1 | CAS number: 10097-02-6 DMBA
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Qualifier:
- according to guideline
- Guideline:
- other: 92/69/EEC, C7 (Preliminary test)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 111 (Hydrolysis as a Function of pH)
- GLP compliance:
- yes
- Transformation products:
- not specified
- pH:
- 9
- Temp.:
- 50 °C
- DT50:
- > 8 760 h
- pH:
- 7
- Temp.:
- 50 °C
- DT50:
- > 8 760 h
- pH:
- 4
- Temp.:
- 50 °C
- DT50:
- > 8 760 h
- Conclusions:
- The substance was found to be hydrolytically stable under acidic, neutral and basic conditions.
- Executive summary:
The study of determination of Hydrolysis as a Function of pH was performed as a preliminary test according to 92/69/EEC, C7 (OECD 111). The substance was found to be hydrolytically stable under acidic, neutral and basic conditions.
The dissipation DT50 of parent compound was established as follow:
DT50 at pH = 4 was more than 8760 hours;
DT50 at pH = 7 was more than 8760 hours;
DT50 at pH = 9 was more than 8760 hours.
Reference
Description of key information
The study of determination of Hydrolysis as a Function of pH was performed as a preliminary test according to 92/69/EEC, C7 (OECD 111). The substance was found to be hydrolytically stable under acidic, neutral and basic conditions.
The dissipation DT50 of parent compound was established as follow:
DT50 at pH = 4 was more than 8760 hours;
DT50 at pH = 7 was more than 8760 hours;
DT50 at pH = 9 was more than 8760 hours.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 8 760 h
- at the temperature of:
- 50 °C
Additional information
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