Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
1992

Materials and methods

Principles of method if other than guideline:
Information from a scientific publication
GLP compliance:
not specified

Test material

1
Chemical structure
Reference substance name:
2-amino-4,6-dinitrophenol
EC Number:
202-544-6
EC Name:
2-amino-4,6-dinitrophenol
Cas Number:
96-91-3
Molecular formula:
C6H5N3O5
IUPAC Name:
2-amino-4,6-dinitrophenol

Test animals

Species:
mouse
Strain:
other: HA/ICR
Sex:
male
Details on test animals or test system and environmental conditions:
36 adult, male HA/ICR mice

Results and discussion

Effect levels
Key result
Sex:
male
Dose descriptor:
LD50
Effect level:
378 mg/kg bw
Based on:
test mat. (total fraction)

Applicant's summary and conclusion

Conclusions:
The LD, for Picramic Acid was 378 mg/kg.
Executive summary:

In an acute oral toxicity study involving 36 adult, male HA/ICR mice the LD, for picramic acid was 378 mg/kg.