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Diss Factsheets
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EC number: 266-442-3 | CAS number: 66669-53-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Water solubility:
- 909.2 g/L
- Conc. based on:
- test mat.
- Incubation duration:
- >= 24 - <= 72 h
- Temp.:
- 20 °C
- pH:
- 6
- Remarks on result:
- completely miscible
- Details on results:
- The test items forms, dissolved in water, a jellylike mass. This makes it difficult to measure volumes. In a preliminary test a quantity of 200.5 mg test item was soluble in 0.2 mL water which is equivalent to 1000 g/L. A subsequent test in the ratio of 5 g test item and 5 g water also showed a clear phase. A test with 10 g test item and 1 g water showed a two phased system (jellylike phase/solid phase). Therefore, the solubility was assumed to be between 1000 g/L and 10000 g/L.
Due to the properties of the test item and the solubility test solutions no value in mass per volume was achievable. Instead a solubility value in g/g was achieved (content of test item per gram of solubility test solution). In Addition, the density of the test solutions was determined to convert the result into the unit “g/L”. The density is determined at 1.55235 g/mL. - Conclusions:
- Water solubility of the test material Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarboxylate at 20 °C was determined as: 909.2 g/L
- Executive summary:
Water solubility of the test material Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarboxylate was investigated at 20 °C with the shake flask method at 20 °C according to OECD Guideline 105. was determined as: 909.2 g/L
Reference
Due to the properties of the test item and the solubility test solutions no value in mass per volume was achievable. Instead a solubility value in g/g was achieved (content of test item per gram of solubility test solution).
Results of individual determinations and mean value
Water solubility test at 20 °C |
Flask A [g/100g] |
Flask B [g/100g] |
Flask C [g/100g] |
Mean value |
|||
Test |
1 |
2 |
1 |
2 |
1 |
2 |
- |
Concentration of Tetrasodium hydrogen 2-phosphonatobutane- 1,2,4-tricarboxylate |
57.43 |
58.47 |
57.92 |
57.60 |
59.91 |
60.11 |
58.6 g/100g |
pH-Value | 6 | 6 | 6 | - |
The relative standard deviation between the single determinations is < 15 % (RSD = 2.0 %).
The validity criteria have therefore been met.
In Addition, the density of the test solutions was determined to convert the result into the unit “g/L”. The density is determined at 1.55235 g/mL.
The water solubility of Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarboxylate in demineralized water at 20 °C is determined to be:
58.6 g/100 g of the test solution (test item and demin. water)
Remark: The used terminology “/100 g test solution” refers to the mixture of dissolved test item and demineralized water. Due to the known content of the test item and the fact that no other components are added, the water content can be calculated as the difference.
Therefore, the result of the test can also be stated as a solubility of the test item of 58.6 g in 41.4 g of demin. water (equal to 1415 g test item per 1000 g water.
Description of key information
Water solubility of the test material Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarboxylate was investigated at 20 °C with the shake flask method at 20 °C according to OECD Guideline 105. was determined as: 909.2 g/L
Key value for chemical safety assessment
- Water solubility:
- 909.2 g/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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