Potassium 2-(4-chloro-2-methylphenoxy)propionate

Short-term toxicity to fish

Administrative data

Endpoint:

short-term toxicity to fish

Type of information:

experimental study

Adequacy of study:

key study

Study period:

06.11.2006 - 10.11.2006

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2006

Report date:

2006

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 203 (Fish, Acute Toxicity Test)

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

Mecoprop

EC Number:

230-386-8

EC Name:

Mecoprop

Cas Number:

7085-19-0

Molecular formula:

C10H11ClO3

IUPAC Name:

2-(4-chloro-2-methylphenoxy)propanoic acid

Test material form:

liquid

Results and discussion

Effect concentrations

Effect concentrations 1

Key result

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

> 100 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Effect concentrations 2

Key result

Duration:

96 h

Dose descriptor:

LC0

Effect conc.:

>= 100 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Effect concentrations 3

Key result

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

> 35.6 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat. (dissolved fraction)

Remarks:

mecoprop as potassium salt

Effect concentrations 4

Key result

Duration:

96 h

Dose descriptor:

LC0

Effect conc.:

>= 35.6 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat. (dissolved fraction)

Remarks:

mecoprop as potassium salt

Applicant's summary and conclusion

Executive summary:

The study was performed according to the OECD Guidelines for Testing of Chemicals (Guideline No 203/ C.1 method) and in compliance with Principles of GLP (Good Laboratory Practice, OECD 1997).

The aim of the study was evaluation of acute toxicity for rainbow trout and determination of LC₅₀, LC₀and LC100 values.

The test material was used in only one concentration (limit test) — 100 mg/L. Because of no mortality was observed in tested fish population the LC_x/96h values are respectively:

- based on nominal concentration of test material the LC₅₀/96 h value is above 100 mg/L, LC₀is equal or above 100 mg/L, LC₁₀₀is above 100 mg/L;

- based on nominal concentration of mecoprop as potassium salt the LC₅₀/96 h value is above 35.6 mg/L, LC₀is equal or above 35.6 mg/L and LC100 is above 35.6 mg/L;

- based on nominal concentration of mecoprop the LC₅₀/96 h value is above 30.2 mg/L, LC₀is equal or above 30.2 mg/L and LC100 is above 30.2 mg/L