Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Acute toxicity: via oral route

Link to relevant study records
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
2 (reliable with restrictions)
Principles of method if other than guideline:
No details on method available
GLP compliance:
not specified
Test type:
acute toxic class method
not specified
not specified
Route of administration:
oral: unspecified
not specified
Dose descriptor:
Effect level:
2 440 mg/kg bw
Endpoint conclusion
Dose descriptor:
2 440 mg/kg bw

Additional information

Justification for classification or non-classification

For the target substance only one value for acute oral toxicity has been reported. In analogy to other isomeric nitroxylenes it can be predicted that the 2 -nitro-p-xylene has a low toxicity. From the datas available it can not be excluded, that the substance could cause cyanosis, like many other nitroaromatic compounds do. Therefore a precautionary classification as harmful in all three application routes seems to be justified.