Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin irritation / corrosion

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Administrative data

skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
supporting study
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference Type:
secondary source
Intensivtherapie akuter Vergiftungen
Klaus Albrecht
Bibliographic source:
GESTIS data base, Institut für Arbeitsschutz der Deutschen Gesetzlichen Unfallversicherung (IFA) Fachbereich 1 Alte Heerstraße 111 53757 Sankt Augustin

Materials and methods

Test guideline
no guideline required
Principles of method if other than guideline:
GLP compliance:
not specified

Test material

Results and discussion

Any other information on results incl. tables

Irrespective of the route of exposure, local effects are predominate. They are characterized by swelling and liquefaction of tissues contacted (colliquative necrosis) which progress rapidly deep into the tissues.

Applicant's summary and conclusion