Registration Dossier
Registration Dossier
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EC number: 201-808-8 | CAS number: 88-19-7
Endpoint summary
Administrative data
Description of key information
Additional information
For all three trophic levels short term studies with o-TSA are available:
A static limit test with Oryzias latipes was performed according to OECD 203 guideline and no fish died at the tested concentration, therefore the 96h-LC50 > 100 mg/L, based on nominal concentrations.
A static test with Daphnia magna was performed according to OECD 202 guideline. The 48h-EC50 = 210 mg/L, based on nominal concentrations.
A static test with Pseudokirchneriella subcapitata was performed according to OECD 201 guideline. The 72h-EC50 for growth rate is 170 mg/L, based on measured concentrations (arithm. mean).
Two long-term studies are availalbe with o-TSA:
A semi-static test with Daphnia magna was performed according to OECD 211 guideline. The NOEC for reproduction was found to be 49 mg/L, based on measured TWA concentrations.
A static test with Pseudokirchneriella subcapitata was performed according to OECD 201 guideline. The 72h-NOEC for growth rate is 7.7 mg/L, based on measured concentrations (arithm. mean).
One study, valid without restrictions, is available with Chloramine T (CAS 127 -65 -1)
(Geerts, 2012). As Chloramine T is instantly converted to p-TSA in the presence of organic material and p-TSA shows similar toxicity to o-TSA, this study can be used for o-TSA as well. Toxicity to microorganisms was determined according to OECD Guideline 209 and the 3h-EC10 was found to be 14 mg/L (nominal). The 3h-EC50 was 37 mg/L (nominal). Converted to o-TSA the 3h-EC10 and and 3h-EC50 are 10.5 mg/L and 27.8 mg/L, respectively.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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