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EC number: 242-053-4 | CAS number: 18169-57-8
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Biodegradation in water, screening tests: No significant biodegradation expected
Key value for chemical safety assessment
Additional information
No data are available for the submission substance, trichloroisobutylsilane. Trichloroisobutylsilane hydrolyses very rapidly in contact with water to give isobutylsilanetriol and hydrogen chloride.
A reliable study conducted according to an appropriate test protocol (EU method C4 -A) is available for trimethoxypropylsilane, whichhydrolyses (half-life 4.6 hours, predicted) to propylsilanetriol and methanol. It is considered appropriate to read across the biodegradation result for trimethoxypropylsilane because its hydrolysis product propylsilanetriol is considered a close structural analogue of isobutylsilanetriol.
This is selected as the key study.The degradation observed in the test is likely to be due to the degradation of methanol, which is expected to biodegrade rapidly, rather than degradation of propylsilanetriol, which is not expected to biodegrade to any significant extent. Therefore, biodegradation of isobutylsilanetriol is expected to be insignificant.
The use of such read-across is supported by evidence that within a category of small molecule silicon-dominated organosilicon compounds, without reactive functional groups in the side chain, there is no evidence of any significant biodegradation in ready biodegradation tests (Data gap filling report for ready biodegradability of silicon-dominated substances PFA.151.004.022A).
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