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Toxicological information

Skin irritation / corrosion

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Administrative data

Endpoint:
skin irritation / corrosion
Remarks:
other: SAR prediction.
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Study period:
2007
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Well-documented
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
publication
Title:
Evaluation of SARs for the prediction of skin irritation/corrosion potential: structural inclusion rules in the BfR decision support system
Author:
Saliner, A. G.; Tsakovska, I.; Pavan, M.; Patlewicz, G.; Worth, A. P.
Year:
2007
Bibliographic source:
SAR QSAR Environ Res, 18, (3-4), 331-42

Materials and methods

Principles of method if other than guideline:
SARs for the prediction of skin irritation/corrosion potential.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
3-(octanoyloxy)propyl octanoate
EC Number:
700-003-3
Cas Number:
56519-71-2
Molecular formula:
C19 H36 O4
IUPAC Name:
3-(octanoyloxy)propyl octanoate

Results and discussion

Applicant's summary and conclusion

Interpretation of results:
other: Unknown
Conclusions:
Prediction of the irritating properties of 1,3-Propanediol Dicaprylate applying TOXmatch was not successful because the outcome of the prediction was "Unknown".