Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 291-807-9 | CAS number: 90480-71-0
Endpoint summary
Administrative data
Description of key information
The key study for acute oral toxicity was read across from the structural analogue hexadecanol (CAS 36653-82-4). It reports an LD50 value >2000mg/kg (Hempstoc k, 1996; rel 1). The key study for acute inhalation toxicity is read across from tetradecanol (CAS 112-72-1). A 1 hour LC50 of >1.5mgl was reported, which is the equivalent of 0.375 mg/l for a 4 hour exposure (Scientific Associates, 1977; rel 2). The acute dermal key study is also read across from tetradecanol, with the LD50 value of ca. 8000 mg/kg (Scientific Associates, 1977; rel 2).
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Dose descriptor:
- LC50
- Value:
- 8 000 mg/m³ air
Additional information
There was no available data for acute toxicity for 1 -pentadecanol. Therefore, key information from structurally related compounds was read across for hazard decisions. For this purpose, data from hexadecanol and tetradecanol was used.
The study for acute inhalation toxicity was selected as read across from 1-tetradecanol as it was the structurally most analogous substance available with the most recent and high reliability information. The reported LC50 value for the study is below the concentration necessary for classification purposes. Furthermore, the saturated vapour concentration (calculated by the reviewer using the ideal gas equation on the basis of the physicocemical properties of 1-tetradecanol) demostrates that the highest theoretically achievable vapour concentration would have been reached or exceeded in this study (4h LC50 value of 0.375 mg/l). Therefore the recorded concentration in the key study represents the highest possible exposure concentration and can be considered for classification purposes.
Justification for classification or non-classification
The data read across from reliable sources of structural analogues suggests that classification and labelling is not required for any of the acute toxicity endpoints, in accordance with CLP (EC regulation 1272/2008).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
