Registration Dossier
Registration Dossier
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EC number: 267-135-7 | CAS number: 67801-15-4
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The acute toxicity of Ebanone to microorganisms is estimated to give a 3-hour EC50 value of 52.5mg/l based on read-across from an appropriate structural analogue.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 52.5 mg/L
- EC10 or NOEC for microorganisms:
- 10 mg/L
Additional information
An appropriate structural analogue (3-methyl-5-(2,2,3-trimethylcyclopent-3-en-1-yl)pent-4-en-2-ol), tradename Ebanol, has been tested for toxicity to microorganisms. The activated sludge respiration inhibition test according to the OECD Guideline No. 209 was performed. Five concentrations in the range 1 to 100 mg/l were tested. The result can be expressed as follows:
EC50 (3 hours) = 52.5 mg/l.
EC10 (3 hours) = 10.0 mg/l.
The aquatic toxicity of the analogue test substance (Ebanol) is anticipated to be similar to that of Ebanone. They are expected to exhibit the same mode of action, non-polar narcosis, and have similar physical-chemical properties (see read-across justification document in section 13 for more details). Therefore, the EC10 and EC50 values of Ebanone are also considered to be 10.0 mg/L and 52.5 mg/L respectively.
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