Registration Dossier
Registration Dossier
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EC number: 208-796-3 | CAS number: 542-02-9
Dissociation constant
Administrative data
Link to relevant study record(s)
Description of key information
The pka value of Acetoguanamine was calculated to be 4.4 +/- 0.4 by the help of the QSAR program ACD/Labs. This is supported by a value for the dissociation constant stated in a publication and a collection of data which is in the same range. Therefore the result of the QSAR calculation can be considered as reliable.
Key value for chemical safety assessment
- pKa at 20°C:
- 4.4
Additional information
The pka value of Acetoguanamine was calculated to be 4.4 +/- 0.4 by the help of the QSAR program ACD/Labs. Furthermore the dissociation constant of Acetoguanamine was stated to be Kb=4.0*10-10 in a publication ("Cyanuric Chloride Derivates. IX. Dissociation Constants of Substituted Melamines and Related Triazines") and in a collection of data ("Produktstudie Guanamine"). Therefore the pka value could be calculated to be 4.6, which is in the same range as the result of the QSAR calculation. Because of this the QSAR result pka= 4.4 +/- 0.4 can be considered as reliable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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