Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 201-058-1 | CAS number: 77-78-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
Start Treatment immediately if exposure is suspected, even if there is no evidence of injury. Redness of the eyes (bloodshot) indicates exposure to very low concentrations of vapour.
Inhalation: If inhaled, remove to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician.
Skin contact: In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Call a physician.
Eye contact: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Call a physician.
Ingestion: If swallowed, do not induce vomiting. Give large quantities of water or activated charcoal slurry. Call a physician immediately. Never give anything by mouth to an unconscious person.
Note: To prepare activated charcoal slurry, suspend 50 grams of activated charcoal in 400 mL of water and mix thoroughly. Give 5 mL/kg, or 350 mLfor an average adult.
Notes to Physicians: Severe symptoms may be delayed for 10 hours or more.
Fire-fighting measures
Evacuate area. Stay upwind and carefully avoid smoke and any possible fumes. Use caution in approaching advanced or massive fires. Product may generate pressure from heat and rupture drums.
Suitable extinguishing media: water mist, foam, dry powder, CO2
Extinguishing media that must not be used for safety reasons: water
Further information: Decontaminate all equipment including personal protective equipment used in firefighting efforts before returning to service. Fire residues and contaminated firefighting media must be disposed of in accordance with the local regulations.
Accidental release measures
In case of leakage close to sources of running water. Evacuate area; keep upwind. Wear full chemical proof suit with hood and breathing air supply to enter spill area. Dike spill: neutralize with dry soda ash followed by water flood, 2-5% solution of ammonia, or dilute caustic soda solution. Let stand until a negative test for DMS is obtained, then transfer to containers for disposal and flush spill area with plenty of water. Do not allow to enter surface waters or groundwater.
Handling and storage
Handling (Personnel): Do not breathe vapor or mist. Do not get in eyes, on skin, or on clothing. Wash thoroughly after handling and before eating or smoking. Avoid contact with any liquid in vicinity of vessels containing DMS; assume liquid is DMS.
Protection against fire and explosion: Keep away from sources of ignition. Take precautionary measures against static discharges. At temperatures above 90°C explosible mixtures in air are formed.
Storage: Store in a well-ventilated area away from heat and flame and out of direct sun. Keep containers closed. Do not store and transport together with strong alkaline materials, strong oxidizers and highly flammable materials. Close empty drums tightly before returning to supplier. Use entire container, do not wash out.
Temperature class: ignition temperature higher than 450°C
Storage class: 3B Combustible liquids
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- UN 1595
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Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- UN 1595
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Marine transport (UN RTDG/IMDG)
- UN number:
- UN 1595
Shipping information
- Proper shipping name and description:
- DIMETHYL SULPHATE
- Chemical name:
- Dimethyl sulphate
- Labels:
- 6.1, 8
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Exposure controls / personal protection
MAK value 0,04 ppm 0,2mg/m3
Engineering Controls: Use with sufficient ventilation to keep employee exposure below recommended limits. Handle in a closed system, if possible.
Wear appropriate protective equipment to prevent any eye or skin contact with liquid or vapor.
Eye/face protection: Wear gas-tight chemical splash goggles with full-length face shield.
Protective clothing: Wear appropriate chemical proof clothing to prevent any contact with liquid or vapor such as gloves, boots and impervious chemical suit with hood. In the event of contamination change protective clothing immediately. Avoid skin contact with the wetted surfaces of the protective gloves
Respirators: Where this is potential for airborne exposure in excess of applicable limits, use approved respirator mask.
Note: Thorough decontamination of personal protective equipment is necessary before removal.
Stability and reactivity
Chemical Stability: Stable. No hazardous reactions, when used as directed.
Incompatibility: Incompatible with strong ammonia solutions and other strong alkaline materials, sodium azide, and strong oxidizers including strong caustic solutions.
Decomposition: Reacts with water or moisture to give methyl hydrogen sulfate and, eventually, sulfuric acid and methanol.
Polymerization: Polymerization will not occur.
Disposal considerations
Product: Examine possibilities for re-utilization. Package product wastes. Close and label the waste receptacles and, likewise, any uncleaned empty containers. Dispose of them at a suitable waste incineration plant in accordance with the official regulations.
Uncleaned packaging: Soiled, empty containers are to be treated in the same way as the contents.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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