Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
2.3 µg/L
Assessment factor:
1 000
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
23 µg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.23 µg/L
Assessment factor:
10 000
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
0.19 mg/L
Assessment factor:
100
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
191 µg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
19.1 µg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
37 µg/kg soil dw

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
PNEC oral
PNEC value:
6.67 mg/kg food
Assessment factor:
300

Additional information

The aquatic toxicity of the test item diisopentyl ether was tested in short-term tests on the toxicity to algae, daphnids and fish. The tests were conducted under GLP and followed OECD TG 201, 202 and 203, respectively. Daphnids were most sensitive with an EC50 after 48h of 2.3 mg/L. The ErC50 for algae was >4.4 mg/L and the LC50 after 96h in fish was 6.8 mg/L. In the algae study, a concentration of 4.4. mg/L was the maximum possible concentration of the test solution preparation (20 mg/L, average of measurement value: 4.4 mg/L).

The effect of the test item on the respiration of activated sewage sludge was assessed in a valid GLP study performed according to OECD TG 209. The EC50 value observed after 3 hours exposure was greater than 19 mg/L.

No information on sediment toxicity and terrestrial toxicity is available.

Conclusion on classification

For diisopentyl ether ecotoxicity data are available for three trophic levels (fish, aquatic invertebrates and alga). From these data the lowest effect values are observed in daphnia (48h EC50 of 2.3 mg/l). According to Regulation (EC) No. 1272/2008 for the Classification, Labelling and Packaging of Substances and Mixtures (CLP), diisopentyl ether is to be classified as hazardous to the aquatic environment category Chronic 2; H411 (Toxic to aquatic life with long lasting effects). According to Directive 67/548/EEC for the Classification, Packaging and Labelling of Dangerous Substances, the substance is to be classified as N; R51/53 (Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment) based on the non-rapid degradability and the daphnia 48h EC50 of 2.3 mg/L.