Registration Dossier
Registration Dossier
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EC number: 204-363-8 | CAS number: 120-00-3
Endpoint summary
Administrative data
Description of key information
Additional information
Stability
Hydrolysis:
Overall OH Rate Constant of 4'-amino-2',5'-diethoxybenzanilide is estimated to be 212.3468 E-12 cm3/molecule-sec at half life of 0.604 Hrs.The estimated half life of the substance indicates that the substance is rapidly hydrolysable.
Phototransformation in water:
No experimental data available. As this study is not a standard information requirement in REACH and there is no indication from the CSA on the need to investigate further the fate and behaviour of the substance (Annex X requirement), no further testing is considered necessary.
Phototransformation in soil:
No experimental data available. As this study is not a standard information requirement in REACH and there is no indication from the CSA on the need to investigate further the fate and behaviour of the substance (Annex X requirement), no further testing is considered necessary.
Biodegradation:
Biodegradation in Water:
Biodegradation of 4'-amino-2',5'-diethoxybenzanilide in water is estimated to be 50% in 38 days. This value suggests that 4'-amino-2',5'-diethoxybenzanilide is readily biodegradable in water. Hence, the substance is not persistent in water.
Biodegradation in Water and Sediment:
According to PBT profiler & EPI suite Biodegradation of 4'-amino-2',5'-diethoxybenzanilide gives 50 % degradation in Water at 38 days & 50% degradation in Sediment at 340 days.These half lives shows that 4'-amino-2',5'-diethoxybenzanilide is readily biodegradable in water while not readily biodegradable in sediment. Hence, 4'-amino-2',5'-diethoxybenzanilide is not persistent in water while persistent in sediment.
Biodegradation in Soil:
The half-life in soil, 75 days, exceeds the EPA criteria of >= 2 months (and <= 6 months). Therefore,4'-amino-2',5'-diethoxybenzanilide is estimated to be persistent in the environment i.e. 4'-amino-2',5'-diethoxybenzanilide is not readily biodegradable in soil. Hence, the substance is persistent in soil.
Bioaccumulation:
The estimated bioconcentration factor (BCF) for Benzamide, 4'-amino-2',5'-diethoxybenzanilide ,17, does not exceed the EPA bioconcentration criteria.The PBT Profiler estimates that 4'-amino-2',5'-diethoxybenzanilide is not expected to bioaccumulate in the food chain because it does not exceed the BCF criteria.
Transport and Distribution:
Adsorption/desoprtion:
Adsorption coefficient (Koc) of 4'-amino-2',5'-diethoxybenzanilide is estimated to be 139.5 at 25°C and it is equivalent to 111.6 at 20°C. This value suggests that 4'-amino-2',5'-diethoxybenzanilide has very strong sorption to soil and sediment i.e. negligible migration potential to groundwater.
Henry's law constant:
Henr'y Law Constant of 4'-amino-2',5'-diethoxybenzanilide is estimated to be 0.00000000000000266 atm m³/mol at 25°C. This value at 25 °C is equivalent to 0.0000000002695245 Pa m³/mole.
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